Studies on psoriasis have also reported an association between increased levels of CCR7 + T lymphocytes and disease persistence [22].Studies have shown that in the synovial microenvironment of RA, the maturity of DCs increases, manifested by high expression of CCR7 and other maturation markers, accompanied by a metabolic shift towards glycolysis [23]. Here, CCR7 is linked to rheumatoid arthritis.