Using available ML algorithms for disease association [Multi-Ontology Enrichment Tool (MOET) disease ontology and ML ingenuity pathway analysis (IPA)], there was computational enrichment in many of the cardiac abnormalities related to the overexpression of the cardiac conduction gene group (Fig. 3F), particularly cardiac arrhythmias, including the most common arrhythmia, atrial fibrillation, and also ventricular fibrillation. The gene discussed is ENSG00000280371; the disease is chronic obstructive pulmonary disease.