In eukaryotic cells, adenosine 5′-triphosphate (ATP)–dependent helicases, RNA binding proteins, chaperonins, and aaRSs are conserved components of biomolecular condensates implicated in various biological processes, such as degenerative disease, circadian clock regulation, and cell fate decisions (24, 50, 51). The gene discussed is CLOCK; the disease is neurodegenerative disease.