The comparison of EMT-TFs expression levels between PDAC and healthy pancreatic tissue revealed significantly elevated mRNA levels of SNAI1, SNAI2, ZEB1 and TWIST in pancreatic cancer tissue, while ZEB2 expression was higher in normal pancreatic tissue (p < 0.05) (Fig 1). The gene discussed is SNAI1; the disease is familial pancreatic carcinoma.