Notably, transcriptome sequencing indicated the significant upregulation of peroxisome proliferator-activated receptor γ (PPARγ) (p < 0.05) (Figure 8K), which was subsequently confirmed by western blot in both 5TGM1 and RPMI 8226 MM cells (p < 0.01) (Figure 8L,M). This evidence concerns the gene PPARG and Miyoshi myopathy.