A comparison of these with the 683 KPTN tumor–upregulated genes (as described in Figure 3A) revealed 130 consistently upregulated genes (Figure 5B), including ECM components (COL4A1, COL4A2, COL12A1, VCAN, etc.)and YAP targets (ANKRD1, AXL, CYR61, F3) (32). The gene discussed is COL12A1; the disease is neoplasm.