A comparison of these with the 683 KPTN tumor–upregulated genes (as described in Figure 3A) revealed 130 consistently upregulated genes (Figure 5B), including ECM components (COL4A1, COL4A2, COL12A1, VCAN, etc.)and YAP targets (ANKRD1, AXL, CYR61, F3) (32). This evidence concerns the gene COL4A2 and neoplasm.