Insulin-like Growth Factor-1 (IGF-1) and Fibroblast Growth Factors (FGFs) are potent neurotrophic factors that support neuronal survival, axonal growth, synaptogenesis, and oligodendrocyte viability and maturation, crucial for both neuronal health and repair of damaged myelin in diseases like MS [74], 75]. This evidence concerns the gene IGF1 and myeloid sarcoma.