Moreover, JAK/STAT and Wnt/β-catenin were found linked through STAT1 recruitment into the promoter of β-catenin under the effect of IFN-γ, promoting NSCs proliferation, self-renewal, and differentiation; co-delivery of IFN-γ and NSCs facilitated their ability of neurological repair after ischemic stroke (Yuan et al., 2020; Zhang et al., 2018). Here, IFNG is linked to ischemic stroke.