Our data also confirmed that patients with PCOS exhibited elevated levels of glucose, insulin, HOMA-IR, triglycerides (TG), hs-CRP, luteinizing hormone (LH), total testosterone, free androgen index (FAI), and dehydroepiandrosterone sulfate (DHEA-S), while levels of high-density lipoprotein cholesterol (HDL-C) and sex hormone-binding globulin (SHBG) were significantly lower. This evidence concerns the gene SHBG and polycystic ovary syndrome.