Glycerol kinase deficiency (GKD), an X-linked disorder causing elevated blood and urinary glycerol levels, can be associated with adrenal abnormalities, particularly in its complex form, involving contiguous gene deletions affecting the GKD locus along with CAH and/or Duchenne muscular dystrophy (DMD) genes (96). This evidence concerns the gene GK and congenital adrenal hyperplasia.