LGALS1 and metastatic malignant neoplasm in the lymph nodes: However, all cases of papillary carcinoma associated with lymph node metastasis were positively stained with galectin-1, while 54.8% (17/31) of negative lymph node metastasis cases were positive for the marker, and 45.2% (14/31) of cases with no lymph node metastasis were negative for galectin-1.