PRKN and Parkinson disease: For the MDSGene dataset, information on AAO was available for 2,537 index patients with a genetic cause of PD (PRKN: n=882, PINK1: n=127, PARK7: n=37, LRRK2: n=800, SNCA: n=80, and VPS35: n=48, GBA1: n=563).