For instance, miR-155 depletion inhibits monocyte infiltration by suppressing CCL2 expression, and KCs exhibit a predominance of the M2 phenotype due to increased CCAAT enhancer-binding proteinβ (C/EBPβ) expression during liver fibrosis associated with NASH and ASH (87, 88). This evidence concerns the gene CCL2 and metabolic dysfunction-associated steatohepatitis.