In addition to the CCL2/CCR2 axis, the CCL20/CCR6 axis can drive hepatic inflammation and fibrosis in patients with alcohol-related steatohepatitis (ASH) and MASH, providing evidence that CCL20/CCR6 mediates inflammatory cell recruitment upon liver injury by promoting infiltration of macrophages and neutrophils (54–56). This evidence concerns the gene CCR2 and metabolic dysfunction-associated steatohepatitis.