MR analysis focused on specific cell types indicated that the L3MBTL3 gene confers a protective effect in monocytes, memory B cells (B-memory), naive B cells (B-naïve), and naive CD8− T cells (CD8− naïve T cells); conversely, in CD8− effector T cells (CD8− effector), CD4+ effector T cells (CD4+ effector), and natural killer cells (NK cells), this gene elevates the risk of OSA (Figure 2D, Supplementary Figures S12-S15, Supplementary Materials 10, 11). This evidence concerns the gene CD4 and obstructive sleep apnea syndrome.