Serum levels of pyroptosis markers (NLRP3, HMGB1, and caspase‐1) and conventional tumor markers, including carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), and cancer antigen 15‐3 (CA15‐3), were measured using enzyme‐linked immunosorbent assay (ELISA) kits. This evidence concerns the gene HMGB1 and neoplasm.