Integrated VOSviewer/CiteSpace analysis generated radar charts that quantify research emphasis across five thematic axes: (1) TFF2/SPEM molecular biology, (2) Helicobacter pylori pathogenesis mechanisms, (3) metaplasia-dysplasia-carcinoma progression, (4) mucosal repair/regeneration pathways, and (5) therapeutic targeting and apoptosis regulation. Here, TFF2 is linked to carcinoma.