GFAP and Parkinson disease: For instance, kaempferol (a flavonol abundant in foods like saffron, apples, and leafy greens) protects against α-synuclein toxicity: in PD models it increases neuronal viability, decreases misfolded α-synuclein aggregates, prevents TH-positive neuron loss, and attenuates astrocyte activation (as indicated by reduced glial fibrillary acidic protein, GFAP) (19).