In the non-DM group, ROC analysis results showed that the AUC values of CRP, ESR, FIB, D-dimer, CAR, and CFR were 0.928 (95%CI 0.900-0.957), 0.873 (95%CI 0.833-0.912), 0.889 (95%CI 0.850-0.929), 0.769 (95%CI 0.710-0.828), 0.931 (95%CI 0.903-0.958), and 0.911 (95%CI 0.878-0.944), respectively. The gene discussed is ESR1; the disease is diabetes mellitus.