These include a maximum eosinophil count ≥1 × 109/L (+5), obstructive airway disease (+3), nasal polyps (+3), cytoplasmic ANCA or anti-proteinase 3-ANCA positivity (-3), extravascular eosinophilic predominant inflammation (+2), mononeuritis multiplex or motor neuropathy not due to radiculopathy (+1), and haematuria (-1). The gene discussed is PRTN3; the disease is radiculopathy.