Studies in human medicine have identified hypoglycorrhachia in bacterial meningitis, CNS disease due to other infectious agents (viral, fungal, protozoal, amoebic), CNS malignancy, hemorrhagic stroke, glucose transporter 1 (GLUT1) receptor deficiency, and non-infectious (aseptic) meningitis (6). The gene discussed is SLC2A1; the disease is infectious meningitis.