Circulating Galectin-3 levels were significantly elevated in patients with T1D compared to healthy controls (median 18.34 [IQR 14.21 to 27.23] versus 13.88 [IQR 10.84 to 17.34] ng/ml; P < 0.0001). The gene discussed is LGALS3; the disease is type 1 diabetes mellitus.