EPAS1 and neuroblastoma: After hypoxic intervention in human neuroblastoma cell lines (SK‐N‐BE(2)c, SH‐SY5Y, SH‐EP, IMR‐32, KCN‐69n), the researchers found that elevated HIF‐2α transcript levels were independent of Akt and mTORC1 signaling and dependent on PI3K/mTORC2 signaling.