NFKB1 and kidney injury: They concluded that endothelial cells have a key role in renoprotection, in which PHD exerts a nondependent function of HIF to regulate NF‐κB negatively, leading to the activation of NF‐κB signaling and HIF prolyl hydroxylase inhibition, leading to modulation of apoptotic responses to suppress inflammation and promote tissue repair to protect against IRI‐ and UUO‐induced kidney injury [55].