We found a genotype difference in TH + staining (p = 0.003) and pair-wise comparisons revealed that TMG-treated TgF344-AD rats have less staining compared to TMG-treated WT rats (p = 0.004), although there were no differences in the saline-treated groups (p = 0.201; Figures 10Di). The gene discussed is TH; the disease is Alzheimer disease.