The outcomes demonstrated that the signal pathway of the intersection targets between JPXK recipe and T2DM majorly touched upon lipid and atherosclerosis, the role of the AGE‐RAGE signaling pathway in diabetic complications, PI3K‐Akt signaling pathway, IL‐17 signaling pathway, fluid shear stress, and atherosclerosis, and endocrine resistance (As shown in Figure 8(a)). This evidence concerns the gene PIK3CA and type 2 diabetes mellitus.