HCCS was found to be significantly upregulated in multiple cancer types, including breast invasive carcinoma (BRCA), kidney chromophobe (KICH), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), and uterine corpus endometrial carcinoma (UCEC) (Figure 1a). The gene discussed is HCCS; the disease is lung adenocarcinoma.