Hypoxia-inducible factor 1α (HIF-1α) upregulates lipid transporters such as CD36, FABP3/7, low-density lipoprotein receptor (LDLR) and FA transport proteins (FATPs), promoting fatty acid influx and accumulation, which enhances the survival of tumor cells (Guo et al., 2011; Bensaad et al., 2014; Pascual et al., 2016; Veglia et al., 2019; Aoki et al., 2022). This evidence concerns the gene LDLR and neoplasm.