To investigate the role of Ccl2 and Ccl8 in pMDMs intrahepatic infiltration and liver fibrosis progression, we treated mice with Bindarit, a dual inhibitor of Ccl2 and Ccl8, during the construction of liver fibrosis model in Tet2ΔMye mice (Fig. S3 G). This evidence concerns the gene CCL8 and Hepatic fibrosis.