ACTA1 and Hepatic fibrosis: In contrast, Tet2ΔAlb mice showed no significant differences in collagen I and α-SMA deposition, HA and Col IV levels, AST and ALT activities, and F4/80+ macrophage infiltration compared with littermate controls (Fig. 1, A–N; and Fig. S1, B–G), indicating that Tet2ΔAlb does not markedly influence liver fibrosis progression.