SQSTM1 and neoplasm: We noted that many of the miRNAs that require p62 for their secretion within exosomes and accumulate in p62-deficient cells (including, but not limited to, miR-33a, miR-122, miR-125a, and miR-339) have been implicated in the suppression of tumor cell growth (Guo et al., 2009; Guo et al., 2013; Tsai et al., 2009; Li et al., 2012; Ninio-Many et al., 2013; Liu et al., 2015; Liu et al., 2016; Liu et al., 2019; Pan et al., 2016; Weber et al., 2016; Karatas et al., 2017; Hui et al., 2018; Weihua et al., 2020).