Point mutations or gene fusions in other genes (e.g., mutations in BRAF, KRAS, APC, and MET genes, or gene fusions in ZEB2‐ALK and SOX5‐RAF1 genes) may be associated with melanoma proliferation or melanoma progression in satellite nevi or LCMN (Martins Da Silva et al. 2019). The gene discussed is SOX5; the disease is large congenital melanocytic nevus.