Moreover, the base excision repair (BER), checkpoint factors (CPF), Fanconi anemia pathway (FA), homologous recombination repair (HRR), and mismatch repair (MMR) pathways showed significant differences, with all five pathways being notably up-regulated in the HRC (p < 0.05) (Fig. 6C). The gene discussed is NR5A2; the disease is Fanconi anemia.