The following investigations were subsequently performed in the context of our patient’s MRI findings: lumbar puncture with opening pressure and CSF studies: cell count, protein, glucose, culture, meningitis/encephalitis panel, IgG index, clear clonal bands, cytology, flow cytometry, MOG, NMO, arbovirus, Bartonella, Lyme, West Nile, Mycoplasma pneumoniae, and Epstein Barr Virus. The gene discussed is MOG; the disease is neuromyelitis optica.