Spearman correlation analysis showed that PD duration was negatively correlated with age, body mass index (BMI), fasting blood glucose, serum creatinine (Scr), peritonitis, catheter-related complications, Self-Rating Depression Scale (SDS) score, and Self-Rating Anxiety Scale (SAS) score, while positively correlated with years of education, DUV, albumin level, number of primary caregivers, and frequency of health education (all p < 0.05). This evidence concerns the gene ALB and major depressive disorder.