NFKB1 and infection: Indeed, ETBF infection in organoids increased Ki67 and phosphorylated β‐catenin (Figure 4F,G), while F. nucleatum in an allograft mouse model upregulated β‐catenin and NF‐κB signaling (Figure 7J–M), validating their roles as microbial modulators of oncogenic pathways [38, 52, 79, 80, 81, 82].