To validate the role of HHT in mediating anti‐AML effects via EWSR1 in vivo, we utilized lentiviral transduction to establish stable EWSR1‐knockdown (shEWSR1) and control (shNC) NB4 and Kasumi‐1 cell lines, confirmed by Western blot analysis showing ~70% EWSR1 reduction (Figure 8A). Here, EWSR1 is linked to acute myeloid leukemia.