Single‐cell analysis indicated that EWSR1 was more highly expressed in AML patients, particularly in HSPC subpopulations including CD34+ HSC, cycling CD34+ HSC, multipotent progenitors (MPP), cycling MPP, and mast cell progenitor (MCP), as well as in myeloid subpopulations such as granulocyte monocyte progenitor (GMP), pro‐neutrophil, CD14+ monocyte, CD16+ monocyte, and dendritic cells (DCs) (Figure S4D–F). Here, EWSR1 is linked to acute myeloid leukemia.