CD58 and diffuse large B-cell lymphoma: Consistent with this, FOXP1 overexpression, a defining feature of the ABC subtype, has been shown to suppress immune response signature and MHC class II expression, further contributing to impaired antigen presentation and T-cell activation (32), while CD58 alterations have been reported to induce PD-L1 and IDO expression, further promoting immune evasion in DLBCL (33).