Alhagi honey polysaccharide AHPN80 effectively promotes the activity of Alcohol Dehydrogenase (ADH) and Aldehyde Dehydrogenase (ALDH), inhibits the activity of Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST), increases High-Density Lipoprotein (HDL) levels, and reduces Low-Density Lipoprotein (LDL), Total Cholesterol (TC), and Triglyceride (TG) levels to alleviate liver damage in Alcoholic Liver Disease (ALD) models. The gene discussed is GPT; the disease is alcoholic liver diseases.