We observed that high DCAF7 aligned with elevated TMB in LUAD, BRCA, stomach and oesophageal carcinoma (STES), sarcoma (SARC), pan‐kidney cohort (KIPAN), STAD and HNSC (Figure 7C and Table S11) and with increased MSI in glioma (GBMLGG), CESC, LUSC, LIHC and CHOL (Figure 7D and Table S12). Here, DCAF7 is linked to central nervous system cancer.