Immunogenomic analyses linked high DCAF7 to CD4+ T‐cell enrichment, broad upregulation of checkpoint genes (PD‐1/PD‐L1, CTLA‐4, TIGIT), and increased tumour mutational burden, microsatellite instability and neoantigen load, suggesting an immune‐evasive phenotype. Here, CD274 is linked to neoplasm.