MGMT and neoplasm: At diagnosis (s = 0), 12-month survival estimates varied significantly with age >60 at diagnosis, preoperative tumor rim volume >20 cm<sup>3</sup>, absence of O<sup>6</sup>-methylguanine-DNA methyltransferase (MGMT) promoter methylation, postoperative KPS ≥70, residual postoperative tumor >1 cm<sup>3</sup>, or biopsy only.