LAMB2 and cancer: Previous studies proposed that NETs may play a key role in the reawakening of dormant cancer cells [13,51,52]. Indeed, a landmark study by Albrengues et al. (2018) experimentally proved that proteases contained in NETs cleave laminin in the extracellular matrix, thereby activating integrin signaling in dormant cancer cells and prompting them to re-enter the cell cycle [18].