IL6 and rheumatoid arthritis: In a study with analysis of SNPs for RA, developed by Amr et al. [24] in an Egyptian population, it was observed that the C allele of the SNP -174 G/C in the IL-6 gene was more frequent in the group of individuals with RA, as well as the G/C and C/C genotypes were more frequent in this same group compared to the control; such differences were statistically significant, with the presence of the C allele associated as a risk factor for the disease.