PDGFRB and metastatic malignant neoplasm in the lymph nodes: However, only a limited number of studies have investigated the expression and functional role of TKIs’ molecular targets, such as PDGFRβ [16,18,23], in AGASAC and corresponding lymph node metastasis [20,22], and to our knowledge PDGFRβ has never been investigated in relation to the histopathological growth patterns of this malignancy.