For the PIT of NMIBC, the cell surface antigens epidermal growth factor receptor (EGFR), Nectin cell adhesion molecule 4 (Nectin-4), and Trophoblast cell surface antigen-2 (TROP-2), amongst others, are conceivable targets because they contribute to tumorigenesis and are overexpressed in BC. The gene discussed is TACSTD2; the disease is breast cancer.