The onset of ARVC is related to inherited genetic mutations, with several genes, particularly those encoding desmosomal proteins such as Plakophilin-2 (PKP2), Desmoplakin (DSP), and Desmoglein-2 (DSG2), implicated in its development [15,16]. The gene discussed is DSG2; the disease is Arrhythmogenic right ventricular dysplasia.