SIRT3 and polycystic ovary syndrome: Treatments such as metformin, berberine, and the Chinese herbal medicine Bu-Shen-Tian-Jing Formula (BSTJF) have been shown to increase SIRT3 expression in GCs, alleviating PCOS symptoms in both KGN cells and PCOS animal models primarily by exerting an antioxidant effect [38,39,40].