Lee et al. used ECO (1-aminoethylimino[bis(N-oleoylcysteinylaminoethyl) propionamide]) NPs to deliver DNApk-cs-targeted siRNA with daily intratumoral injections for 5 consecutive days, combined with radiotherapy, and achieved significant results in the treatment of gliomas [40]. This evidence concerns the gene PRKDC and glioma.