Furthermore, to implement the cytoprotection concept in eye therapy, in particular in corneal neovascularization counteraction, perceiving BPC 157 corneal ulcer healing capability as a whole was carried out, respecting the antiangiogenic agents, endostatin, PAI-1, PEDF, angiostatin, TSP-1/2, IFN-α, as a class. This evidence concerns the gene COL18A1 and corneal ulcer.