SERPINE1 and glaucoma: PAI-1 exhibited distinctive relations (corneal ulcer healing ↑ ↔ corneal neovascularization ↓↑ (pro-angiogenic at physiological concentrations and anti-angiogenic at higher concentrations)↔intraocular pressure not affected (0) or ↑ (PAI-1 contributes to glaucoma pathogenesis)↔linked to other avascular tissues healing (i.e., tendon) ↓).