Commonly, comparing corneal ulcer healing with the “triad” (corneal healing/corneal neovascularization/intraocular pressure relation) and healing in another avascular tissue like tendon, under a cytoprotection umbrella, these agents, ascorbate, fibronectin, hyaluronic acid, MMP inhibitors, EGF, FGF, NGF, and insulin/IGF-1, all revealed the particular “triad” relations, and a connection or no connection with tendon healing. The gene discussed is INS; the disease is corneal infection.