FOXP3 and acute respiratory distress syndrome: Recent research in a rat model of LPS-induced ARDS demonstrated that FMT modulates the expression of retinoic acid receptor-related orphan receptor gamma t (RORγt) and Forkhead box P3 (Foxp3), reestablishing the Th17/Treg cell ratio through inhibition of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway, which in turn resulted in improvements in both intestinal and lung injury [133].