Women with infertility more frequently recognized different folate forms (87.2% vs. 72.3%; p = 0.018), knew the role of the MTHFR gene (77.7% vs. 39.4%; p < 0.001), and initiated supplementation ≥3 months before conception (88.3% vs. 47.9%; p < 0.001). This evidence concerns the gene MTHFR and Infertility.