CCL2 and rheumatoid arthritis: More specifically, they showed that the adipose tissue from both RA patients and obese animal models releases high amounts of chemokines capable of recruiting neutrophils (e.g., IL-8/MIP2, CXCL1, and CXCL5) and monocytes (e.g., IL-6, IL-1β, and CCL2) [82].