Experimental depletion of Vγ1+ cells in an animal CRS model reduced eosinophilic inflammation and suppressed T2-associated cytokines (IL-4, IL-5, and IL-13) and GATA3 expression [15], indicating that defined γδ subsets can potentiate T2-biased inflammation. The gene discussed is GATA3; the disease is congenital rubella syndrome.